Program Description
Program Faculty
Agenda
Faculty Presentations
Accepted Abstracts
Jackson Hole


Day 1 - Thursday, September 25, 2008

5:00 - 5:15 PM Welcome and Overview of Program
Kenneth E. Sherman, MD, PhD
University of Cincinnati College of Medicine
5:15 - 5:35 PM Epidemiology of HIV in 2008
John T. Brooks, MD
Centers for Disease Control and Prevention
5:35 - 6:00 PM HIV Treatment Guidelines, 2008
Judith Feinberg, MD
University of Cincinnati College of Medicine
6:00 - 6:25 PM Epidemiology of Liver Disease in HIV
Richard K. Sterling, MD, MSc
Virginia Commonwealth University
6:25 - 6:40 PM

SELECTED ORAL PRESENTATION
Decreasing Liver-Related Mortality Associated With a Decreasing Prevalence of HCV Coinfection: Data From the HIV Atlanta VA Cohort Study (HAVACS)
David Rimland, MD
Atlanta VA Medical Center

6:40 - 6:55 PM

SELECTED ORAL PRESENTATION
A 4-Year Follow-Up of a Cohort of HIV-Positive Cirrhotic Patients
Paula Tuma, MD
University Complutense Hospital Carlos III

7:00 - 8:30 PM Poster Session and Welcome Reception

Day 2 - Friday, September 26, 2008

7:30 - 8:05 AM Liver Pathology in HIV
Zachary D. Goodman, MD, PhD
Armed Forces Institute of Pathology
8:05 - 8:20 AM

SELECTED ORAL PRESENTATION
Comparison of FIB-4 and APRI in HIV-HCV Coinfected Patients With Normal and Elevated ALT
Amy Shah , MD
Virginia Commonwealth University

8:20 - 8:35 AM

SELECTED ORAL PRESENTATION
Liver Fibrosis in Patients With Chronic Hepatitis C and Persistently Normal Transaminases - Influence of HIV Infection in the HAART Era
Vincent Soriano, MD, PhD
University Complutense Hospital Carlos III

8:35 - 8:50 AM

SELECTED ORAL PRESENTATION
Risk Factors for Advanced Liver Fibrosis in HIV-Infected Individuals: Role of Metabolic Abnormalities
Pablo Barreiro, MD, PhD
University Complutense Hospital Carlos II

8:50 - 9:10 AM Panel Discussion: Role of Noninvasive Markers of Liver Injury in 2008
Zachary D. Goodman, MD, PhD
Vincent Soriano, MD, PhD
Pablo Barreiro, MD, PhD
9:10 - 9:30 AM Break
9:30 - 10:00 AM Immunopathogenesis of Liver Injury in HIV
Margaret J. Koziel, MD
Beth Israel Deaconess Medical Center
10:00 - 10:20 AM New Forms of Liver Injury in HIV Infected Patients
Richard M. Green, MD
Northwestern University-Feinberg School of Medicine
10:20 - 10:45 AM Steatosis/Insulin Resistance in HIV
Marshall J. Glesby, MD, PhD
Weill Cornell Medical College
10:45 - 11:00 AM

SELECTED ORAL PRESENTATION
Unexplained Severe Portal Hypertension in HIV Patients: A New Clinical Entity?
Vincent Soriano, MD, PhD
University Complutense Hospital Carlos III

11:00 - 11:25 AM Role of Alcohol in Mediation of Hepatic Injury in HIV-Infected Patients
Craig J. McClain, MD
University of Louisville
11:25 - 11:50 AM Panel Discussion: Liver Injury
Margaret J. Koziel, MD
Richard M. Green, MD
Marshall J. Glesby, MD, PhD
Craig J. McClain, MD
11:50 AM - 1:00 PM Clinical Case Lunch Breakout: Meet the Professor
1:00 - 1:20 PM HIV and HCV Virology
Jason T. Blackard, PhD
University of Cincinnati College of Medicine
1:20 - 1:45 PM HCV and HBV Mutation and Evolution
Stuart Ray, MD
Johns Hopkins University School of Medicine
1:45 - 2:10 PM Effect of Host Genetic Polymorphisms
Matthew J. Dolan, MD, FACP
San Antonio Military Medical Center
2:10 - 2:35 PM Mechanisms of ART Liver Injury
Timothy J. Davern II, MD
University of California at San Francisco
2:35 - 2:50 PM

SELECTED ORAL PRESENTATION
Apoptosis in HCV and HCV/HIV Coinfected Patients: Evaluation Using M30 Serum Caspase Assay
Philippe J. Zamor, MD
University of Cincinnati College of Medicine

2:50 - 3:10 PM Break
3:10 - 3:40 PM HCV Targets and Therapeutic Agents
Raymond T. Chung, MD
Harvard Medical School
3:40 - 4:10 PM FDA Drug Development Issues in Patients With Liver Disease
Russell D. Fleischer, PA-C, MPH
US Food and Drug Administration
4:10 - 4:25 PM SELECTED ORAL PRESENTATION
HCV Relapse After Peg-Interferon (IFN) Plus Ribavirin (RBV) Therapy: Is 12-Week Assessment Upon Completion of Treatment Enough to Determine Sustained HCV Clearance?
Pablo Barreiro, MD, PhD
University Complutense Hospital Carlos III
4:25 - 4:40 PM SELECTED ORAL PRESENTATION
HCV Treatment Eligibility in ERCHIVES (Electronically Retrieved Cohort of HCV Infected Veterans)
Adeel A. Butt, MD, MS
University of Pittsburgh School of Medicine
4:40 - 4:50 PM Closing Remarks
Kenneth E. Sherman, MD, PhD

Day 3 - Saturday, September 27, 2008

7:00 - 7:30 AM Continental Breakfast
7:30 - 7:55 AM HBV/HIV Epidemiology and Natural History
Vincent Soriano, MD, PhD
University Complutense Hospital Carlos III
7:55 - 8:25 AM HBV Treatment in HIV
Barbara H. McGovern, MD
Tufts University
8:25 - 8:40 AM

SELECTED ORAL PRESENTATION
Cytokine Expression During Chronic Versus Occult Hepatitis B Virus Infection in HIV Coinfected Individuals
Christina M. Martin, BS
University of Cincinnati College of Medicine

8:40 - 8:55 AM

SELECTED ORAL PRESENTATION
Outcome of Chronic Hepatitis Delta in Patients With and Without HIV Infection in the HAART Era
Paula Tuma, MD
University Complutense Hospital Carlos III

8:55 - 9:25 AM Research Questions in HCV and HBV Management:
Panel Discussion

Barbara H. McGovern, MD
Raymond T. Chung, MD
Vincent Soriano MD, PhD
9:25 - 9:45 AM Break
9:45 - 10:05 AM Progression of Decompensated Liver Disease
in Patients With HIV

Margaret V. Ragni, MD, MPH
University of Pittsburgh Medical School
10:05 - 10:25 AM Selection and Outcome of Liver Transplant
Candidates With HIV

Peter G. Stock, MD, PhD
University of California at San Francisco
10:25 - 10:40 AM

SELECTED ORAL PRESENTATION
HCV Infection and Cirrhosis Are Key Risk Factors for Thrombocytopenia in the Era of Potent Antiretroviral Therapy
Kristen M. Marks, MD
Weill Cornell Medical College

10:40 - 11:00 AM

Panel Discussion: End-Stage Liver Disease
Margaret V. Ragni, MD, MPH
Peter G. Stock, MD, PhD

  11:00 - 11:10 AM Break
11:10 - 11:30 AM Management Issues in HIV-infected Patients With Unhealthy Alcohol Use
Jeffrey H. Samet, MD, MA, MPH
Boston University Schools of Medicine and Public Health
11:30 - 12:00 PM Psychiatric Issues in HIV Patients With Liver Disease
Andrew F. Angelino, MD, DFAPA
Johns Hopkins University School of Medicine
12:00 - 12:15 PM

SELECTED ORAL PRESENTATION
Impact of Treating Depression in Hepatitis C/HIV Coinfected Patients: A Significant Benefit from Early Screening and Treatment
Laveeza Bhatti, MD, PhD
AIDS Healthcare Foundation

12:15 - 1:00 PM Clinical Case Lunch Breakout: Meet the Professor
1:00 - 1:20 PM Panel Discussion: Drug/Psychological Management Issues
Andrew F. Angelino, MD, DFAPA
Jeffrey H Samet, MD, MA, MPH
1:20 - 1:50 PM NIH Research Agenda
Susan W. Brobst, PhD
National Institute of Allergy and Infectious Diseases
1:50 - 2:00 PM Closing Remarks
Kenneth E. Sherman, MD, PhD

 
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